The Buffalo Bills are a heavy favorite winning 96.0% of simulations over the Tennessee Titans. Josh Allen is averaging 187.0 passing yards and 3.4 TDs per simulation and Devin Singletary is projected for 55.0 rushing yards and a 75.0% chance of having at least 1 rushing TD. In the 4.0% of simulations where Tennessee Titans wins, Ryan Tannehill averages 1.73 TD passes vs 0.68 interceptions, while in losses he has a ratio of 1.3 TDs to 1.52 interceptions. Derrick Henry averages 159.0 rushing yards and 1.46 rushing TDs when Tennessee Titans wins and 97.0 yards and 0.59 TDs in losses. Buffalo Bills has a 97.0% chance of forcing more turnovers than they commit. Positive turnover margin helps them win 97.0% of the time.
| Tennessee Titans | | Buffalo Bills | | |
|---|
| All Games | 8-7-2 | All Games | 8-10-1 | Buffalo Bills |
| Road Games | 50-30-10 | Home Games | 4-6-1 | No Edge |
| When Underdog | 4-4-2 | When Favored | 8-10-1 | Buffalo Bills |
| Non-Division Opp | 5-4-2 | Non-Division Opp | 6-5-1 | Buffalo Bills |
| Opp .500+ Record | 3-3-1 | Opp .500+ Record | 2-5-1 | Buffalo Bills |
| Tennessee Titans | | Buffalo Bills | | |
|---|
| All Games | 10-8-0 | All Games | 9-9-1 | |
| Road Games | 40-40-00 | Home Games | 4-5-0 | No Edge |
| When Underdog | 6-1-0 | When Favored | 7-7-1 | |
| Non-Division Opp | 6-6-0 | Non-Division Opp | 5-7-0 | |
| Opp .500+ Record | 61-62-0 | Opp .500+ Record | 53-66-0 | |
| Tennessee Titans | | Buffalo Bills | | |
|---|
| All Totals (O-U-P) | 5-12-0 | All Totals (O-U-P) | 6-13-0 | UNDER |
| On Road | 2-7-0 | At Home | 5-5-0 | UNDER |
| All Totals Last Season | 7-11-0 | All Totals Last Season | 10-9-0 | UNDER |
| On Road Last Season | 6-2-0 | At Home Last Season | 4-6-0 | OVER |
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