September 13, 2025 12:00 PM EST

San Francisco 49ers vs New Orleans Saints 09/14/2025

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Expect a close game with the San Francisco 49ers winning 49.0% of simulations, and the New Orleans Saints 50.0% of simulations. In close games, turnover margin is especially important. The San Francisco 49ers commit fewer turnovers in 64.0% of simulations and they go on to win 61.0% when they take care of the ball. The New Orleans Saints wins 72.0% of the simulations in which they commit fewer turnovers. Christian McCaffrey is averaging 52.0 rushing yards per sim. If he can have a great game with better than average rushing yards and at least a 1 rushing TD (22.0% chance) then he helps his team win 72%. Alvin Kamara is averaging 54.0 rushing yards per sim. If he can have a great game with better than average rushing yards and at least a 1 rushing TD (15.0% chance) then he helps his team win 80%.

CURRENT SEASON: We advise relying on these trends after the first 3 weeks of the season.

San Francisco 49ersATS RECORDNew Orleans SaintsATS RECORDATS EDGE
All Games 1-0-0All Games 0-1-0San Francisco 49ers
Road Games 10-00-00Home Games 0-1-0San Francisco 49ers
When Favored 1-0-0When Underdog 0-1-0San Francisco 49ers
Non-Division Opp 0-0-0Non-Division Opp 0-1-0No Edge
Opp Under .500 0-0-0Opp .500+ Record 0-0-0No Edge

LAST SEASON: We advise factoring for these trends for the first 3 to 6 weeks of the Current Season.

San Francisco 49ersATS RECORDNew Orleans SaintsATS RECORDATS EDGE
All Games 5-12-0All Games 7-10-0No Edge
Road Games 10-70-00Home Games 4-5-0 No Edge
When Favored 5-8-0When Underdog 5-7-0No Edge
Non-Division Opp 4-7-0Non-Division Opp 3-8-0No Edge
Opp Under .500 39-53-0Opp Under .500 46-58-0No Edge

OVER-UNDER TRENDS

San Francisco 49ersO-U-P RECORDNew Orleans SaintsO-U-P RECORDO-U EDGE
All Totals (O-U-P) 0-1-0All Totals (O-U-P) 0-1-0UNDER
On Road 0-1-0At Home 0-1-0UNDER
All Totals Last Season 11-6-0All Totals Last Season 8-9-0OVER
On Road Last Season 6-2-0At Home Last Season 4-5-0OVER

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