December 21, 2025 5:42 AM EST

Buffalo Bills vs Cleveland Browns 12/21/2025

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The Buffalo Bills are a heavy favorite winning 80.0% of simulations over the Cleveland Browns. Josh Allen is averaging 227.0 passing yards and 1.44 TDs per simulation and James Cook is projected for 76.0 rushing yards and a 43.0% chance of having at least 1 rushing TD. In the 20.0% of simulations where Cleveland Browns wins, Shedeur Sanders averages 1.38 TD passes vs 0.76 interceptions, while in losses he has a ratio of 0.85 TDs to 1.79 interceptions. Quinshon Judkins averages 96.0 rushing yards and 0.54 rushing TDs when Cleveland Browns wins and 48.0 yards and 0.16 TDs in losses. The Buffalo Bills have a 83.0% chance of forcing more turnovers than they commit. Positive turnover margin helps them win 86.0% of the time.

CURRENT SEASON: We advise relying on these trends after the first 3 weeks of the season.

Buffalo BillsATS RECORDCleveland BrownsATS RECORDATS EDGE
All Games 7-7-0All Games 4-9-1No Edge
Road Games 40-30-00Home Games 3-3-0 No Edge
When Favored 5-7-0When Underdog 3-7-1No Edge
Non-Division Opp 5-4-0Non-Division Opp 3-7-0No Edge
Opp Under .500 1-4-0Opp .500+ Record 1-6-0No Edge

LAST SEASON: We advise factoring for these trends for the first 3 to 6 weeks of the Current Season.

Buffalo BillsATS RECORDCleveland BrownsATS RECORDATS EDGE
All Games 12-7-1All Games 4-13-0No Edge
Road Games 50-50-00Home Games 2-6-0 No Edge
When Favored 9-5-1When Underdog 4-10-0No Edge
Non-Division Opp 9-4-1Non-Division Opp 2-9-0No Edge
Opp Under .500 86-49-7Opp .500+ Record 39-91-0No Edge

OVER-UNDER TRENDS

Buffalo BillsO-U-P RECORDCleveland BrownsO-U-P RECORDO-U EDGE
All Totals (O-U-P) 7-7-0All Totals (O-U-P) 7-6-1OVER
On Road 2-5-0At Home 4-2-1UNDER
All Totals Last Season 13-6-1All Totals Last Season 7-9-1OVER
On Road Last Season 6-4-0At Home Last Season 3-5-0No Edge

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