November 26, 2025 5:17 PM EST

San Francisco 49ers vs Cleveland Browns 11/30/2025

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The San Francisco 49ers are a solid favorite with a 72.0% chance to beat the Cleveland Browns. Christian McCaffrey is projected for 58.0 rushing yards and a 19.0% chance of having at least 1 rushing TD. In the 28.0% of simulations where Cleveland Browns wins, Shedeur Sanders averages 0.62 TD passes vs 0.39 interceptions, while in losses he has a ratio of 0.36 TDs to 0.7 interceptions. Quinshon Judkins averages 74.0 rushing yards and 0.37 rushing TDs when Cleveland Browns wins and 42.0 yards and 0.12 TDs in losses. The San Francisco 49ers has a 72.0% chance of forcing more turnovers than they commit. Positive turnover margin helps them win 84.0% of the time.

CURRENT SEASON: We advise relying on these trends after the first 3 weeks of the season.

San Francisco 49ersATS RECORDCleveland BrownsATS RECORDATS EDGE
All Games 7-5-0All Games 4-6-1No Edge
Road Games 50-20-00Home Games 3-1-0 No Edge
When Favored 6-2-0When Underdog 3-5-1No Edge
Non-Division Opp 4-3-0Non-Division Opp 3-4-0No Edge
Opp Under .500 3-1-0Opp .500+ Record 1-4-0No Edge

LAST SEASON: We advise factoring for these trends for the first 3 to 6 weeks of the Current Season.

San Francisco 49ersATS RECORDCleveland BrownsATS RECORDATS EDGE
All Games 5-12-0All Games 4-13-0No Edge
Road Games 10-70-00Home Games 2-6-0 No Edge
When Favored 5-8-0When Underdog 4-10-0No Edge
Non-Division Opp 4-7-0Non-Division Opp 2-9-0No Edge
Opp Under .500 39-53-0Opp Under .500 17-91-0No Edge

OVER-UNDER TRENDS

San Francisco 49ersO-U-P RECORDCleveland BrownsO-U-P RECORDO-U EDGE
All Totals (O-U-P) 7-5-0All Totals (O-U-P) 6-5-0OVER
On Road 5-2-0At Home 3-2-0OVER
All Totals Last Season 11-6-0All Totals Last Season 7-9-1OVER
On Road Last Season 6-2-0At Home Last Season 3-5-0OVER

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