The San Francisco 49ers are a solid favorite with a 73.0% chance to beat the Carolina Panthers. Jeff Wilson Jr. is projected for 54.0 rushing yards and a 39.0% chance of having at least 1 rushing TD. In the 26.0% of simulations where Carolina Panthers wins, Baker Mayfield averages 0.63 TD passes vs 0.86 interceptions, while in losses he has a ratio of 0.34 TDs to 1.54 interceptions. Christian McCaffrey averages 137.0 rushing yards and 1.23 rushing TDs when Carolina Panthers wins and 67.0 yards and 0.32 TDs in losses. The San Francisco 49ers has a 77.0% chance of forcing more turnovers than they commit. Positive turnover margin helps them win 83.0% of the time.
| San Francisco 49ers | | Carolina Panthers | | |
|---|
| All Games | 13-7-0 | All Games | 9-8-0 | |
| Road Games | 40-50-00 | Home Games | 5-4-0 | No Edge |
| When Favored | 13-5-0 | When Underdog | 8-5-0 | |
| Non-Division Opp | 6-7-0 | Non-Division Opp | 4-7-0 | |
| Opp Under .500 | 3-1-0 | Opp .500+ Record | 4-3-0 | San Francisco 49ers |
| San Francisco 49ers | | Carolina Panthers | | |
|---|
| All Games | 12-8-0 | All Games | 4-13-0 | |
| Road Games | 80-40-00 | Home Games | 1-7-0 | No Edge |
| When Favored | 6-7-0 | When Underdog | 3-7-0 | |
| Non-Division Opp | 9-4-0 | Non-Division Opp | 2-9-0 | |
| Opp Under .500 | 73-47-0 | Opp .500+ Record | 29-85-0 | |
| San Francisco 49ers | | Carolina Panthers | | |
|---|
| All Totals (O-U-P) | 10-10-0 | All Totals (O-U-P) | 8-9-0 | UNDER |
| On Road | 4-5-0 | At Home | 4-5-0 | UNDER |
| All Totals Last Season | 9-11-0 | All Totals Last Season | 7-10-0 | UNDER |
| On Road Last Season | 5-7-0 | At Home Last Season | 3-5-0 | UNDER |
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