October 06, 2025 4:25 AM EST

San Francisco 49ers vs Los Angeles Rams 10/02/2025

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The Los Angeles Rams are a heavy favorite winning 79.0% of simulations over the San Francisco 49ers. Matthew Stafford is averaging 268.0 passing yards and 1.6 TDs per simulation and Kyren Williams is projected for 77.0 rushing yards and a 48.0% chance of having at least 1 rushing TD. In the 21.0% of simulations where San Francisco 49ers wins, Mac Jones averages 0.98 TD passes vs 0.47 interceptions, while in losses he has a ratio of 0.6 TDs to 0.95 interceptions. Christian McCaffrey averages 73.0 rushing yards and 0.34 rushing TDs when San Francisco 49ers wins and 43.0 yards and 0.12 TDs in losses. Los Angeles Rams has a 68.0% chance of forcing more turnovers than they commit. Positive turnover margin helps them win 88.0% of the time.

CURRENT SEASON: We advise relying on these trends after the first 3 weeks of the season.

San Francisco 49ersATS RECORDLos Angeles RamsATS RECORDATS EDGE
All Games 3-2-0All Games 3-2-0No Edge
Road Games 30-00-00Home Games 2-1-0San Francisco 49ers
When Underdog 1-0-0When Favored 3-1-0San Francisco 49ers
Division Opp 2-1-0Division Opp 0-1-0No Edge
Opp .500+ Record 1-2-0Opp .500+ Record 1-2-0No Edge

LAST SEASON: We advise factoring for these trends for the first 3 to 6 weeks of the Current Season.

San Francisco 49ersATS RECORDLos Angeles RamsATS RECORDATS EDGE
All Games 5-12-0All Games 11-7-1No Edge
Road Games 10-70-00Home Games 5-5-1 No Edge
When Underdog 0-4-0When Favored 4-3-0No Edge
Division Opp 1-5-0Division Opp 4-2-0No Edge
Opp .500+ Record 31-115-0Opp Under .500 49-45-0No Edge

OVER-UNDER TRENDS

San Francisco 49ersO-U-P RECORDLos Angeles RamsO-U-P RECORDO-U EDGE
All Totals (O-U-P) 3-2-0All Totals (O-U-P) 3-2-0OVER
On Road 2-1-0At Home 1-2-0No Edge
All Totals Last Season 11-6-0All Totals Last Season 9-10-0OVER
On Road Last Season 6-2-0At Home Last Season 5-5-0OVER

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