September 17, 2025 2:44 PM EST

Chicago Cubs vs Pittsburgh Pirates 9/17/2025

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The Chicago Cubs are 40-35 on the road this season and are heavy favorites to beat the Pittsburgh Pirates who are 42-34 at home. The Cubs have a better than 55% chance of winning based on 10,000 game simulations generated one play at a time by the AccuScore Simulation Supercomputer. Cubs starter Matthew Boyd is forecasted to have a better game than Pirates starter Johan Oviedo. Matthew Boyd has a 64% chance of having a Quality Start (QS) while Johan Oviedo has a 43% chance of a QS. If Matthew Boyd has a quality start the Cubs has a 76% chance of winning. His simulated strikeout to walk ratio is 4.3 and he has a 31% chance of having a 5 to 1 K/BB ratio. When he has a 5/1 ratio the Cubs win 64%. In Johan Oviedo quality starts the Pirates win 58%. He has a 17% chance of having a 5 to 1 K/BB ratio and if he does his team wins 58% of simulations. In simulations we tracked the batter for each team that was most productive based his average hits, walks and RBI per simulation. The most productive batter for the Pittsburgh Pirates is Andrew McCutchen who averaged 1.82 hits+walks+RBI. He has a 27% chance of having a big game with 3+ Hits, Walks, RBI and if he has a big game the Pirates have a 49% chance of winning. The most productive batter for the Chicago Cubs is Michael Busch who averaged 2.17 hits+walks+RBI. He has a 37% chance of having a big game with 3+ Hits, Walks, RBI and if he has a big game the Cubs have a 77% chance of winning.

CURRENT SEASON: We advise relying on these trends after the first 6 to 8 weeks of the season. UNITS EDGE FAVORS: Pittsburgh Pirates

Chicago CubsRECORDPittsburgh PiratesRECORDUNITS EDGE
Record on the Road40-35, 53% 98Record at Home42-34, 55% 796Pittsburgh Pirates
VS Pittsburgh Pirates8-3, 73% 218VS Chicago Cubs3-8, 27% -394Chicago Cubs
vs Team Under .50050-25, 67% 658vs Team .500 or Better37-53, 41% -468Chicago Cubs
Record as Road Favorite26-18, 59% 83Record as Home Underdog27-19, 59% 1289Pittsburgh Pirates
When Matthew Boyd Starts15-15, 50% -552When Johan Oviedo Starts3-4, 43% -9Pittsburgh Pirates

PAST 30 DAYS: We advise incorporating these trends along with the current Season after the first 6 to 8 weeks. UNITS EDGE FAVORS: Pittsburgh Pirates

Chicago CubsRECORDPittsburgh PiratesRECORDUNITS EDGE
Record on the Road8-5, 62% 107Record at Home8-5, 62% 252Pittsburgh Pirates
VS Pittsburgh Pirates1-0, 100% 82VS Chicago Cubs0-1, 0% -100Chicago Cubs
vs Team .500 or Better1-3, 25% -218vs Team .500 or Better7-6, 54% 254Pittsburgh Pirates
Record as Road Favorite7-5, 58% -33Record as Home Underdog5-5, 50% 109Pittsburgh Pirates
When Matthew Boyd Starts2-3, 40% -178When Johan Oviedo Starts2-4, 33% -113Pittsburgh Pirates

OVER-UNDER TRENDS

Chicago CubsRECORDPittsburgh PiratesRECORDO-U EDGE
OVER-UNDER ON ROAD35-37, 49% OverOVER-UNDER AT HOME31-39, 44% OverUNDER
ROAD OVER-UNDER PAST 30 DAYS3-9, 25% OverROAD OVER-UNDER PAST 30 DAYS5-7, 42% OverUNDER
ROAD OVER-UNDER LAST SEASON40-36, 53% OverROAD OVER-UNDER LAST SEASON43-38, 53% OverUNDER
OVER-UNDER IN Matthew Boyd STARTS10-18, 36% OverOVER-UNDER IN Johan Oviedo STARTS3-4, 43% OverN/A

ACCUSCORE ADVISOR: AccuScore simulates every game thousands of times one play at a time. We are the industry standard in sports forecasting and the only company to be paid for sports picks and predictions by the biggest sports companies in the world. Our newest product, the AccuScore Advisor, provides Side Value, Money Line and Over-Under picks for every MLB game and rates them as One, Two, Three or Four Star picks. Three and Four Star picks have delivered over +10,000 units of profit the past 2 seasons. Visit AccuScore.com to find out what AccuScore\'s Advisor recommends for this game. The following trends are AccuScore\'s RIGHT-WRONG records and units (+/-) when making picks involving these teams.

SIDE VALUE (Current Season) - Chicago Cubs Road Games: 38-37, 51% -1017 Pittsburgh Pirates Home Games: 36-40, 47% -227 SIDE VALUE (PAST 30 DAYS) - Chicago Cubs Road Games: 7-6, 54% -178 Pittsburgh Pirates Home Games: 4-9, 31% -481

MONEY LINE (Current Season) - Chicago Cubs Road Games: 43-32, 57% +117 Pittsburgh Pirates Home Games: 40-36, 53% -414 MONEY LINE (PAST 30 DAYS) - Chicago Cubs Road Games: 10-3, 77% +471 Pittsburgh Pirates Home Games: 8-5, 62% -19

OVER-UNDER RECORD (Current Season) - Chicago Cubs Road Games: 40-22, 65% + 1580 Pittsburgh Pirates Home Games: 32-32, 50% -320 OVER-UNDER RECORD (PAST 30 DAYS) - Chicago Cubs Road Games: 7-4, 64% + 260 Pittsburgh Pirates Home Games: 7-4, 64% + 260

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