July 22, 2025 4:03 PM EST

Baltimore Orioles vs Cleveland Guardians 7/22/2025

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The Cleveland Guardians are 23-24 at home this season and are heavy favorites to beat the Baltimore Orioles who are 22-30 on the road this season. The Guardians have a better than 60% chance of winning based on 10,000 game simulations generated one play at a time by the AccuScore Simulation Supercomputer. Guardians starter Joey Cantillo is forecasted to have a better game than Orioles starter Brandon Young. Joey Cantillo has a 47% chance of having a Quality Start (QS) while Brandon Young has a 26% chance of a QS. If Joey Cantillo has a quality start the Guardians has a 86% chance of winning. His simulated strikeout to walk ratio is 6.1 and he has a 37% chance of having a 5 to 1 K/BB ratio. When he has a 5/1 ratio the Guardians win 66%. In Brandon Young quality starts the Orioles win 60%. He has a 19% chance of having a 5 to 1 K/BB ratio and if he does his team wins 60% of simulations. In simulations we tracked the batter for each team that was most productive based his average hits, walks and RBI per simulation. The most productive batter for the Cleveland Guardians is Jose Ramirez who averaged 2.92 hits+walks+RBI. He has a 55% chance of having a big game with 3+ Hits, Walks, RBI and if he has a big game the Guardians have a 75% chance of winning. The most productive batter for the Baltimore Orioles is Ramon Laureano who averaged 2.02 hits+walks+RBI. He has a 33% chance of having a big game with 3+ Hits, Walks, RBI and if he has a big game the Orioles have a 45% chance of winning.

CURRENT SEASON: We advise relying on these trends after the first 6 to 8 weeks of the season. UNITS EDGE FAVORS: Cleveland Guardians

Baltimore OriolesRECORDCleveland GuardiansRECORDUNITS EDGE
Record on the Road22-30, 42% -635Record at Home23-24, 49% -575Cleveland Guardians
VS Cleveland Guardians2-2, 50% -38VS Baltimore Orioles2-2, 50% 4Cleveland Guardians
vs Team Under .50018-22, 45% -744vs Team Under .50028-13, 68% 960Cleveland Guardians
Record As Road Underdog18-24, 43% -346Record As Home Favorite16-10, 62% 79Cleveland Guardians
When Brandon Young Starts0-5, 0% -500When Joey Cantillo Starts2-1, 67% 137Cleveland Guardians

PAST 30 DAYS: We advise incorporating these trends along with the current Season after the first 6 to 8 weeks. UNITS EDGE FAVORS: Cleveland Guardians

Baltimore OriolesRECORDCleveland GuardiansRECORDUNITS EDGE
Record on the Road5-6, 45% -18Record at Home4-9, 31% -586Baltimore Orioles
VS Cleveland Guardians0-1, 0% -100VS Baltimore Orioles1-0, 100% 74Cleveland Guardians
vs Team Under .5008-6, 57% 336vs Team .500 or Better7-9, 44% -169Baltimore Orioles
Record As Road Underdog4-6, 40% -108Record As Home Favorite3-3, 50% -77Cleveland Guardians
When Brandon Young Starts0-3, 0% -300When Joey Cantillo Starts2-1, 67% 137Cleveland Guardians

OVER-UNDER TRENDS

Baltimore OriolesRECORDCleveland GuardiansRECORDO-U EDGE
OVER-UNDER ON ROAD18-33, 35% OverOVER-UNDER AT HOME22-23, 49% OverUNDER
ROAD OVER-UNDER PAST 30 DAYS5-6, 45% OverROAD OVER-UNDER PAST 30 DAYS8-5, 62% OverOVER
ROAD OVER-UNDER LAST SEASON44-35, 56% OverROAD OVER-UNDER LAST SEASON41-38, 52% OverUNDER
OVER-UNDER IN Brandon Young STARTS2-3, 40% OverOVER-UNDER IN Joey Cantillo STARTS2-1, 67% OverN/A

ACCUSCORE ADVISOR: AccuScore simulates every game thousands of times one play at a time. We are the industry standard in sports forecasting and the only company to be paid for sports picks and predictions by the biggest sports companies in the world. Our newest product, the AccuScore Advisor, provides Side Value, Money Line and Over-Under picks for every MLB game and rates them as One, Two, Three or Four Star picks. Three and Four Star picks have delivered over +10,000 units of profit the past 2 seasons. Visit AccuScore.com to find out what AccuScore\'s Advisor recommends for this game. The following trends are AccuScore\'s RIGHT-WRONG records and units (+/-) when making picks involving these teams.

SIDE VALUE (Current Season) - Baltimore Orioles Road Games: 26-26, 50% -266 Cleveland Guardians Home Games: 26-21, 55% +261 SIDE VALUE (PAST 30 DAYS) - Baltimore Orioles Road Games: 6-5, 55% +143 Cleveland Guardians Home Games: 8-5, 62% +213

MONEY LINE (Current Season) - Baltimore Orioles Road Games: 28-24, 54% -240 Cleveland Guardians Home Games: 31-16, 66% +752 MONEY LINE (PAST 30 DAYS) - Baltimore Orioles Road Games: 6-5, 55% -97 Cleveland Guardians Home Games: 9-4, 69% +311

OVER-UNDER RECORD (Current Season) - Baltimore Orioles Road Games: 35-13, 73% + 2070 Cleveland Guardians Home Games: 21-18, 54% + 120 OVER-UNDER RECORD (PAST 30 DAYS) - Baltimore Orioles Road Games: 6-3, 67% + 270 Cleveland Guardians Home Games: 6-7, 46% -170

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