May 16, 2025 4:36 PM EST

Chicago White Sox vs Chicago Cubs 5/16/2025

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The Chicago Cubs are 12-10 at home this season and are heavy favorites to beat the Chicago White Sox who are 5-17 on the road this season. The Cubs have a better than 60% chance of winning based on 10,000 game simulations generated one play at a time by the AccuScore Simulation Supercomputer. Cubs starter Cade Horton ® is forecasted to have a better game than White Sox starter Shane Smith. Cade Horton ® has a 47% chance of having a Quality Start (QS) while Shane Smith has a 26% chance of a QS. If Cade Horton ® has a quality start the Cubs has a 88% chance of winning. His simulated strikeout to walk ratio is 3.4 and he has a 32% chance of having a 5 to 1 K/BB ratio. When he has a 5/1 ratio the Cubs win 79%. In Shane Smith quality starts the White Sox win 57%. He has a 12% chance of having a 5 to 1 K/BB ratio and if he does his team wins 57% of simulations. In simulations we tracked the batter for each team that was most productive based his average hits, walks and RBI per simulation. The most productive batter for the Chicago Cubs is Kyle Tucker who averaged 3.05 hits+walks+RBI. He has a 54% chance of having a big game with 3+ Hits, Walks, RBI and if he has a big game the Cubs have a 83% chance of winning. The most productive batter for the Chicago White Sox is Luis Robert Jr. who averaged 2.15 hits+walks+RBI. He has a 36% chance of having a big game with 3+ Hits, Walks, RBI and if he has a big game the White Sox have a 35% chance of winning.

CURRENT SEASON: We advise relying on these trends after the first 6 to 8 weeks of the season. UNITS EDGE FAVORS: Chicago Cubs

Chicago White SoxRECORDChicago CubsRECORDUNITS EDGE
Record on the Road5-17, 23% -746Record at Home12-10, 55% -124Chicago Cubs
VS Chicago Cubs0-0 No GamesVS Chicago White Sox0-0 No GamesN/A
vs Team .500 or Better4-21, 16% -1351vs Team Under .5006-3, 67% 144Chicago Cubs
Record As Road Underdog5-17, 23% -746Record As Home Favorite8-7, 53% -203Chicago Cubs
When Shane Smith Starts1-4, 20% -205When Cade Horton ® Starts14-6, 70% 702Chicago Cubs

PAST 30 DAYS: We advise incorporating these trends along with the current Season after the first 6 to 8 weeks. UNITS EDGE FAVORS: Chicago Cubs

Chicago White SoxRECORDChicago CubsRECORDUNITS EDGE
Record on the Road5-11, 31% -146Record at Home8-6, 57% -22Chicago Cubs
VS Chicago Cubs0-0 No GamesVS Chicago White Sox0-0 No GamesN/A
vs Team .500 or Better5-14, 26% -426vs Team Under .5009-6, 60% 89Chicago Cubs
Record As Road Underdog5-11, 31% -146Record As Home Favorite4-5, 44% -301Chicago White Sox
When Shane Smith Starts1-3, 25% -105When Cade Horton ® Starts4-4, 50% 20Chicago Cubs

OVER-UNDER TRENDS

Chicago White SoxRECORDChicago CubsRECORDO-U EDGE
OVER-UNDER ON ROAD8-14, 36% OverOVER-UNDER AT HOME13-9, 59% OverUNDER
ROAD OVER-UNDER PAST 30 DAYS6-10, 38% OverROAD OVER-UNDER PAST 30 DAYS8-6, 57% OverUNDER
ROAD OVER-UNDER LAST SEASON37-40, 48% OverROAD OVER-UNDER LAST SEASON33-47, 41% OverOVER
OVER-UNDER IN Shane Smith STARTS0-5, 0% OverOVER-UNDER IN Cade Horton ® STARTS14-6, 70% OverN/A

ACCUSCORE ADVISOR: AccuScore simulates every game thousands of times one play at a time. We are the industry standard in sports forecasting and the only company to be paid for sports picks and predictions by the biggest sports companies in the world. Our newest product, the AccuScore Advisor, provides Side Value, Money Line and Over-Under picks for every MLB game and rates them as One, Two, Three or Four Star picks. Three and Four Star picks have delivered over +10,000 units of profit the past 2 seasons. Visit AccuScore.com to find out what AccuScore\'s Advisor recommends for this game. The following trends are AccuScore\'s RIGHT-WRONG records and units (+/-) when making picks involving these teams.

SIDE VALUE (Current Season) - Chicago White Sox Road Games: 11-11, 50% -21 Chicago Cubs Home Games: 10-12, 45% -421 SIDE VALUE (PAST 30 DAYS) - Chicago White Sox Road Games: 8-8, 50% +58 Chicago Cubs Home Games: 6-8, 43% -319

MONEY LINE (Current Season) - Chicago White Sox Road Games: 17-5, 77% +199 Chicago Cubs Home Games: 13-9, 59% -5 MONEY LINE (PAST 30 DAYS) - Chicago White Sox Road Games: 11-5, 69% -59 Chicago Cubs Home Games: 7-7, 50% -228

OVER-UNDER RECORD (Current Season) - Chicago White Sox Road Games: 14-8, 64% + 520 Chicago Cubs Home Games: 11-8, 58% + 220 OVER-UNDER RECORD (PAST 30 DAYS) - Chicago White Sox Road Games: 10-6, 62% + 340 Chicago Cubs Home Games: 6-5, 55% + 50

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