April 21, 2025 7:04 AM EST

Chicago White Sox vs Boston Red Sox 4/21/2025

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The Boston Red Sox are 4-3 at home this season and are solid favorites to beat the Chicago White Sox who are 0-6 on the road this season. The Red Sox have a better than 55% chance of winning based on 10,000 game simulations generated one play at a time by the AccuScore Simulation Supercomputer. Red Sox starter Walker Buehler is forecasted to have a better game than White Sox starter Jonathan Cannon. Walker Buehler has a 53% chance of having a Quality Start (QS) while Jonathan Cannon has a 36% chance of a QS. If Walker Buehler has a quality start the Red Sox has a 80% chance of winning. His simulated strikeout to walk ratio is 2.5 and he has a 7% chance of having a 5 to 1 K/BB ratio. When he has a 5/1 ratio the Red Sox win 59%. In Jonathan Cannon quality starts the White Sox win 61%. He has a 16% chance of having a 5 to 1 K/BB ratio and if he does his team wins 61% of simulations. In simulations we tracked the batter for each team that was most productive based his average hits, walks and RBI per simulation. The most productive batter for the Boston Red Sox is Wilyer Abreau who averaged 2.41 hits+walks+RBI. He has a 40% chance of having a big game with 3+ Hits, Walks, RBI and if he has a big game the Red Sox have a 74% chance of winning. The most productive batter for the Chicago White Sox is Chase Meidroth who averaged 3.99 hits+walks+RBI. He has a 95% chance of having a big game with 3+ Hits, Walks, RBI and if he has a big game the White Sox have a 37% chance of winning.

CURRENT SEASON: We advise relying on these trends after the first 6 to 8 weeks of the season. UNITS EDGE FAVORS: Boston Red Sox

Chicago White SoxRECORDBoston Red SoxRECORDUNITS EDGE
Record on the Road0-6, 0% -600Record at Home4-3, 57% 19Boston Red Sox
VS Boston Red Sox2-1, 67% 181VS Chicago White Sox1-2, 33% -158Chicago White Sox
vs Team Under .5002-4, 33% -119vs Team Under .5006-3, 67% 157Boston Red Sox
Record As Road Underdog0-6, 0% -600Record As Home Favorite3-3, 50% -70Boston Red Sox
When Jonathan Cannon Starts0-3, 0% -300When Walker Buehler Starts1-1, 50% -32Boston Red Sox

LAST SEASON: We advise focusing on these trends in the first month of the season. UNITS EDGE FAVORS: Boston Red Sox

Chicago White SoxRECORDBoston Red SoxRECORDUNITS EDGE
Record on the Road18-63, 22% -3180Record at Home38-43, 47% -1143Boston Red Sox
VS Boston Red Sox3-4, 43% 88VS Chicago White Sox4-3, 57% -110Chicago White Sox
vs Team .500 or Better24-92, 21% -5070vs Team Under .50042-24, 64% 1043Boston Red Sox
Record As Road Underdog18-62, 22% -3080Record As Home Favorite24-30, 44% -1332Boston Red Sox
When Jonathan Cannon Starts8-13, 38% 116When Walker Buehler Starts9-8, 53% -82Chicago White Sox

OVER-UNDER TRENDS

Chicago White SoxRECORDBoston Red SoxRECORDO-U EDGE
OVER-UNDER ON ROAD2-4, 33% OverOVER-UNDER AT HOME2-4, 33% OverUNDER
ROAD OVER-UNDER PAST 30 DAYS2-4, 33% OverROAD OVER-UNDER PAST 30 DAYS2-4, 33% OverUNDER
ROAD OVER-UNDER LAST SEASON37-40, 48% OverROAD OVER-UNDER LAST SEASON35-42, 45% OverUNDER
OVER-UNDER IN Jonathan Cannon STARTS1-2, 33% OverOVER-UNDER IN Walker Buehler STARTS1-1, 50% OverN/A

ACCUSCORE ADVISOR: AccuScore simulates every game thousands of times one play at a time. We are the industry standard in sports forecasting and the only company to be paid for sports picks and predictions by the biggest sports companies in the world. Our newest product, the AccuScore Advisor, provides Side Value, Money Line and Over-Under picks for every MLB game and rates them as One, Two, Three or Four Star picks. Three and Four Star picks have delivered over +10,000 units of profit the past 2 seasons. Visit AccuScore.com to find out what AccuScore\'s Advisor recommends for this game. The following trends are AccuScore\'s RIGHT-WRONG records and units (+/-) when making picks involving these teams.

SIDE VALUE (Current Season) - Chicago White Sox Road Games: 3-3, 50% -79 Boston Red Sox Home Games: 4-3, 57% +19 SIDE VALUE (Last Season) - Chicago White Sox Road Games: 42-39, 52% +500 Boston Red Sox Home Games: 37-44, 46% -1244

MONEY LINE (Current Season) - Chicago White Sox Road Games: 6-0, 100% +258 Boston Red Sox Home Games: 3-4, 43% -170 MONEY LINE (Last Season) - Chicago White Sox Road Games: 64-17, 79% +1365 Boston Red Sox Home Games: 36-45, 44% -1787

OVER-UNDER RECORD (Current Season) - Chicago White Sox Road Games: 4-2, 67% + 180 Boston Red Sox Home Games: 0-4, 0% -440 OVER-UNDER RECORD (LAST SEASON) - Chicago White Sox Road Games: 41-34, 55% + 360 Boston Red Sox Home Games: 41-35, 54% + 250

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